An outbreak of bird flu has been confirmed in turkeys at a farm near Louth in Lincolnshire.
More than 5,000 birds have been affected with the H5N8 strain of the disease.
A 3km protection zone and a 10km surveillance zone is now in place around the farm to prevent the disease spreading.
Most of the birds at the site have died and officials say the rest will be culled.
The Department for Environment, Food and Rural Affairs (Defra) confirmed the outbreak and said the disease has been affecting animals across Europe.
Chief Veterinary Officer Nigel Gibbens said immediate steps had been taken to stop the spread and reassure the public.
"Public Health England (PHE) has confirmed that the risk to public health is very low and the Food Standards Agency has said that bird flu does not pose a food safety risk for UK consumers," he said.
PHE said Avian flu was "primarily a disease of birds", and there have never been any recorded cases of H5N8 in humans.
A "prevention zone" was set up across England, Scotland and Wales last week after a virulent strain of the virus was picked up in Europe.
All poultry and captive bird keepers were advised to house their birds.
Defra said theses measures remain in place and advised people to report any suspected cases.
A detailed investigation is in progress to determine the most likely source of the outbreak.
The most recent previous case of avian influenza confirmed in the UK was at a poultry farm in Dunfermline on 13 January 2016.
The outbreak is not expected to have any impact on the supplies of turkeys or other birds over Christmas.
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